Jan 28 – Feb 2 | SPIE Photonics West | San Francisco
Nanoscope President and CSO, Dr. Samarendra Mohanty will make an oral presentation and poster presentations on January 29th, 2023.
Oral Presentation:
Abstract Title: Functionalizing inner retina with multi-characteristic opsin arrested further degeneration and functional deterioration
Abstract Number: 12366-10
Session Name: 3. Clinical Applications
Session Date: Sunday, January 29, 2023
Presentation Time: 11:40 a.m.-12:00 p.m. PT
Location: Moscone Center, Room 101 (Level 1 South Lobby)
Presenter: Dr. Samarendra Mohanty, President and Chief Scientific Officer of Nanoscope Therapeutics
In addition to highlighting the benefits of MCO gene therapy, Dr. Mohanty will discuss the results of intravitreally delivered AAV-carried MCO-010 in multiple mice models of retinal degeneration, including retinitis pigmentosa and Stargardt disease, that showed arrest of further retinal degeneration as evaluated by optical coherence tomography (OCT), electroretinogram (ERG) and immuno-histochemistry (IHC).
Poster Presentation:
Abstract Title: OCT-guided variable spot electrophysiology platform for correlated structural and functional assessment of optogenetic intervention
Abstract Number: 12366-24
Session Name: BiOS poster session
Session Date: Sunday, January 29, 2023
Presentation Time: 5:30-7:00 p.m. PT
Location: Moscone Center, Level 2 West
Dr. Mohanty will detail the development of image-guided spatially resolved functional assessment of retina using OCT-guided variable-spot stimulated electroretinogram (vsERG). The OCT-vsERG platform is currently used to monitor diseased areas in retina of patients with Stargardt macular degeneration and to measure functional changes after optogenetic therapy.
Conference website