{"id":9812,"date":"2025-10-22T07:02:03","date_gmt":"2025-10-22T12:02:03","guid":{"rendered":"https:\/\/nanostherapeutics.com\/?p=9812"},"modified":"2025-10-22T18:30:15","modified_gmt":"2025-10-22T23:30:15","slug":"nanoscope-therapeutics-announces-durable-3-year-vision-improvements-from-remain-study-of-mco-010-in-retinitis-pigmentosa","status":"publish","type":"post","link":"https:\/\/nanostherapeutics.com\/ar\/2025\/10\/22\/nanoscope-therapeutics-announces-durable-3-year-vision-improvements-from-remain-study-of-mco-010-in-retinitis-pigmentosa\/","title":{"rendered":"\u0623\u0639\u0644\u0646\u062a \u0634\u0631\u0643\u0629 \u0646\u0627\u0646\u0648\u0633\u0643\u0648\u0628 \u062b\u064a\u0631\u0627\u0628\u064a\u0648\u062a\u0643\u0633 \u0639\u0646 \u062a\u062d\u0633\u0646\u0627\u062a \u0628\u0635\u0631\u064a\u0629 \u0645\u0633\u062a\u062f\u0627\u0645\u0629 \u0644\u0645\u062f\u0629 3 \u0633\u0646\u0648\u0627\u062a \u0645\u0646 \u062f\u0631\u0627\u0633\u0629 REMAIN \u0644\u0639\u0642\u0627\u0631 MCO-010 \u0641\u064a \u0639\u0644\u0627\u062c \u0627\u0644\u062a\u0647\u0627\u0628 \u0627\u0644\u0634\u0628\u0643\u064a\u0629 \u0627\u0644\u0635\u0628\u0627\u063a\u064a"},"content":{"rendered":"<div data-elementor-type=\"wp-post\" data-elementor-id=\"9812\" class=\"elementor elementor-9812\" data-elementor-post-type=\"post\">\n\t\t\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-6d5ad04f elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"6d5ad04f\" data-element_type=\"section\" data-e-type=\"section\">\r\n\t\t\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\r\n\t\t\t\t\r\n\t\t\t\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-5bf9bdef\" data-id=\"5bf9bdef\" data-element_type=\"column\" data-e-type=\"column\">\r\n\r\n\t\t\t\t\r\n\t\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\r\n\t\t\t\t\t\t\t\t\t\t\r\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-e3a8c93 elementor-widget elementor-widget-text-editor\" data-id=\"e3a8c93\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<h3 style=\"text-align: center;\"><em>\u0623\u0638\u0647\u0631\u062a \u0646\u062a\u0627\u0626\u062c \u062f\u0631\u0627\u0633\u0629 REMAIN \u062a\u062d\u0633\u0646\u0627\u064b \u0645\u0633\u062a\u062f\u0627\u0645\u0627\u064b \u0641\u064a \u062d\u062f\u0629 \u0627\u0644\u0628\u0635\u0631 \u0628\u0645\u0642\u062f\u0627\u0631 3 \u0623\u0633\u0637\u0631 \u0645\u0642\u0627\u0631\u0646\u0629\u064b \u0628\u0627\u0644\u062e\u0637 \u0627\u0644\u0623\u0633\u0627\u0633\u064a \u0639\u0644\u0649 \u0645\u062f\u0627\u0631 152 \u0623\u0633\u0628\u0648\u0639\u0627\u064b \u0644\u062f\u0648\u0627\u0621 MCO-010 \u0644\u062f\u0649 \u0627\u0644\u0645\u0631\u0636\u0649 \u0627\u0644\u0630\u064a\u0646 \u064a\u0639\u0627\u0646\u0648\u0646 \u0645\u0646 \u0641\u0642\u062f\u0627\u0646 \u0634\u062f\u064a\u062f \u0641\u064a \u0627\u0644\u0628\u0635\u0631 \u0646\u062a\u064a\u062c\u0629 \u0627\u0644\u062a\u0647\u0627\u0628 \u0627\u0644\u0634\u0628\u0643\u064a\u0629 \u0627\u0644\u0635\u0628\u0627\u063a\u064a\u060c \u0628\u0627\u0644\u0625\u0636\u0627\u0641\u0629 \u0625\u0644\u0649 \u0633\u0644\u0627\u0645\u0629 \u0627\u0633\u062a\u062e\u062f\u0627\u0645\u0647.<\/em><\/h3><h3><em>\u062a\u0634\u0643\u0644 \u0647\u0630\u0647 \u0627\u0644\u0628\u064a\u0627\u0646\u0627\u062a \u0627\u0644\u0623\u0633\u0627\u0633 \u0627\u0644\u0633\u0631\u064a\u0631\u064a \u0644\u0637\u0644\u0628 \u062a\u0631\u062e\u064a\u0635 \u0627\u0644\u0645\u0646\u062a\u062c\u0627\u062a \u0627\u0644\u0628\u064a\u0648\u0644\u0648\u062c\u064a\u0629 \u0627\u0644\u0645\u062a\u062c\u062f\u062f\u060c \u0648\u0627\u0644\u0630\u064a \u0628\u062f\u0623 \u0641\u064a \u064a\u0648\u0646\u064a\u0648 2025\u060c \u0648\u0627\u0644\u0630\u064a \u0645\u0646 \u0627\u0644\u0645\u062d\u062a\u0645\u0644 \u0623\u0646 \u064a\u0643\u0648\u0646 \u0623\u0648\u0644 \u0639\u0644\u0627\u062c \u0648\u0631\u0627\u062b\u064a \u0636\u0648\u0626\u064a \u0645\u0639\u062a\u0645\u062f \u0645\u0646 \u0625\u062f\u0627\u0631\u0629 \u0627\u0644\u063a\u0630\u0627\u0621 \u0648\u0627\u0644\u062f\u0648\u0627\u0621 \u0627\u0644\u0623\u0645\u0631\u064a\u0643\u064a\u0629<\/em><\/h3><h3 style=\"text-align: center;\"><em>\u062a\u064f\u0638\u0647\u0631 \u0645\u0646\u0635\u0629 MCO \u0625\u0645\u0643\u0627\u0646\u0627\u062a \u0648\u0627\u0639\u062f\u0629 \u0643\u0639\u0644\u0627\u062c \u0628\u0635\u0631\u064a \u0648\u0631\u0627\u062b\u064a \u0644\u0645\u0631\u0629 \u0648\u0627\u062d\u062f\u0629\u060c \u0644\u0627 \u064a\u0631\u062a\u0628\u0637 \u0628\u0645\u0631\u0636 \u0645\u0639\u064a\u0646\u060c \u0644\u0644\u0645\u0631\u0636\u0649 \u0627\u0644\u0630\u064a\u0646 \u064a\u0639\u0627\u0646\u0648\u0646 \u0645\u0646 \u0641\u0642\u062f\u0627\u0646 \u0634\u062f\u064a\u062f \u0641\u064a \u0627\u0644\u0628\u0635\u0631<\/em><\/h3><p>\u00a0<\/p><p>DALLAS, Oct. 22, 2025&#8211; <a href=\"http:\/\/nanostherapeutics.com\/ar\/\" target=\"_blank\" rel=\"nofollow noopener\">\u0634\u0631\u0643\u0629 \u0646\u0627\u0646\u0648\u0633\u0643\u0648\u0628 \u0644\u0644\u0639\u0644\u0627\u062c\u0627\u062a<\/a>, a biotechnology company committed to developing and commercializing novel disease-agnostic therapies for patients with photoreceptor loss and vision impairment due to retinal degeneration, today announced positive three-year follow-up data from the\u00a0REMAIN study, the long-term extension of the Phase 2b\/3\u00a0RESTORE trial\u00a0evaluating\u00a0MCO-010, the Company&#8217;s proprietary optogenetic therapy for patients with\u00a0retinitis pigmentosa (RP).<\/p><p><b>\u0646\u062a\u0627\u0626\u062c \u0627\u0644\u0628\u0642\u064a\u0629\u00a0<\/b><b>\u0623\u0638\u0647\u0631\u062a \u062a\u062d\u0633\u064a\u0646\u0627\u062a \u0628\u0635\u0631\u064a\u0629 \u0645\u0633\u062a\u062f\u0627\u0645\u0629 \u0648\u0630\u0627\u062a \u062f\u0644\u0627\u0644\u0629 \u0633\u0631\u064a\u0631\u064a\u0629 \u0628\u0639\u062f \u062d\u0642\u0646\u0629 \u0648\u0627\u062d\u062f\u0629 \u062f\u0627\u062e\u0644 \u0627\u0644\u062c\u0633\u0645 \u0627\u0644\u0632\u062c\u0627\u062c\u064a \u0645\u0646 MCO-010\u060c \u0645\u0639 \u0627\u0644\u062d\u0641\u0627\u0638 \u0639\u0644\u0649 \u0645\u0633\u062a\u0648\u0649 \u0623\u0645\u0627\u0646 \u0648\u062a\u062d\u0645\u0644 \u062c\u064a\u062f\u064a\u0646 \u0639\u0644\u0649 \u0645\u062f\u0627\u0631 \u062b\u0644\u0627\u062b \u0633\u0646\u0648\u0627\u062a.<\/b><\/p><p>&#8220;The sustained visual gains demonstrated over three years are truly remarkable for this population,&#8221; said\u00a0<a href=\"https:\/\/nanostherapeutics.com\/ar\/who-we-are\/allen-ho-vac\/\" target=\"_blank\" rel=\"nofollow noopener\">\u0623\u0644\u064a\u0646 \u0633\u064a. \u0647\u0648\u060c \u062f\u0643\u062a\u0648\u0631 \u0641\u064a \u0627\u0644\u0637\u0628\u060c \u0645\u062f\u064a\u0631 \u0623\u0628\u062d\u0627\u062b \u0627\u0644\u0634\u0628\u0643\u064a\u0629 \u0641\u064a \u0645\u0633\u062a\u0634\u0641\u0649 \u0648\u064a\u0644\u0632 \u0644\u0644\u0639\u064a\u0648\u0646 \u0648\u0643\u0628\u064a\u0631 \u0627\u0644\u0645\u0633\u062a\u0634\u0627\u0631\u064a\u0646 \u0627\u0644\u0637\u0628\u064a\u064a\u0646 \u0644\u0634\u0631\u0643\u0629 \u0646\u0627\u0646\u0648\u0633\u0643\u0648\u0628<\/a>. &#8220;These patients typically lose about 1.5 lines of vision every five years and often hit legal blindness as early as age 20. The ability to not just slow loss but restore visual function for several years represents a significant therapeutic advance.&#8221;<\/p><p><b>\u0623\u0647\u0645 \u0627\u0644\u0646\u062a\u0627\u0626\u062c \u0645\u0646 \u062f\u0631\u0627\u0633\u0629 \u0627\u0644\u0645\u062a\u0627\u0628\u0639\u0629 \u0637\u0648\u064a\u0644\u0629 \u0627\u0644\u0623\u0645\u062f REMAIN \u0627\u0644\u062a\u064a \u0627\u0633\u062a\u0645\u0631\u062a 152 \u0623\u0633\u0628\u0648\u0639\u064b\u0627<\/b>\u00a0<b>\u00a0\u064a\u0630\u0627\u0643\u0631<\/b>\u00a0<b>:<\/b><\/p><ul type=\"disc\"><li><b>\u0641\u0639\u0627\u0644\u064a\u0629 \u0637\u0648\u064a\u0644\u0629 \u0627\u0644\u0623\u0645\u062f:<\/b>\u00a0\u062d\u0627\u0641\u0638 \u0627\u0644\u0645\u0631\u0636\u0649 \u0639\u0644\u0649 \u0645\u062a\u0648\u0633\u0637 \u062a\u062d\u0633\u0646 \u0641\u064a \u062d\u062f\u0629 \u0627\u0644\u0628\u0635\u0631 \u0627\u0644\u0645\u0635\u062d\u062d\u0629 (BCVA) \u0645\u0646 \u062e\u0637 \u0627\u0644\u0623\u0633\u0627\u0633 \u0628\u0645\u0642\u062f\u0627\u0631 0.3 LogMAR \u062a\u0642\u0631\u064a\u0628\u064b\u0627 (\u0645\u0627 \u064a\u0639\u0627\u062f\u0644 \u062b\u0644\u0627\u062b\u0629 \u0623\u0633\u0637\u0631 \u0623\u0648 15 \u062d\u0631\u0641\u064b\u0627 \u0639\u0644\u0649 \u0645\u062e\u0637\u0637 \u0631\u0624\u064a\u0629 ETDRS \u0627\u0644\u0642\u064a\u0627\u0633\u064a)\u060c \u062d\u062a\u0649 \u0627\u0644\u0623\u0633\u0628\u0648\u0639 152. \u062a\u064f\u0638\u0647\u0631 \u0645\u0644\u0641\u0627\u062a \u062a\u0639\u0631\u064a\u0641 BCVA-AREA \u062a\u062d\u062a \u0627\u0644\u0645\u0646\u062d\u0646\u0649 (AUC) \u0639\u0628\u0631 \u0643\u0644 \u0645\u0646 RESTORE \u0648REMAIN \u0645\u0643\u0627\u0633\u0628 \u0641\u064a \u0627\u0644\u0631\u0624\u064a\u0629 \u0623\u0643\u0628\u0631 \u0628\u062e\u0645\u0633\u0629 \u0623\u0636\u0639\u0627\u0641 \u0645\u0642\u0627\u0631\u0646\u0629 \u0628\u0627\u0644\u0639\u0644\u0627\u062c \u0627\u0644\u0648\u0647\u0645\u064a.<\/li><li><b>\u0645\u0633\u062a\u0648\u0649 \u0623\u0645\u0627\u0646 \u062c\u064a\u062f:<\/b>\u00a0\u0644\u0645 \u064a\u062a\u0645 \u0627\u0644\u0625\u0628\u0644\u0627\u063a \u0639\u0646 \u0623\u064a \u0623\u062d\u062f\u0627\u062b \u0636\u0627\u0626\u0631\u0629 \u062e\u0637\u064a\u0631\u0629 \u0641\u064a \u0627\u0644\u0639\u064a\u0646 \u0628\u064a\u0646 \u0627\u0644\u0645\u0631\u0636\u0649 \u0627\u0644\u0630\u064a\u0646 \u062e\u0636\u0639\u0648\u0627 \u0644\u0644\u0639\u0644\u0627\u062c.<\/li><li><b>\u0627\u0644\u0642\u062f\u0631\u0629 \u0639\u0644\u0649 \u0627\u0644\u062a\u062d\u0645\u0644 \u0639\u0644\u0649 \u0627\u0644\u0645\u062f\u0649 \u0627\u0644\u0637\u0648\u064a\u0644:<\/b>\u00a0\u0644\u0645 \u062a\u062a\u0637\u0644\u0628 \u0633\u0648\u0649 \u062d\u0627\u0644\u0629 \u0627\u0644\u062a\u0647\u0627\u0628 \u062e\u0641\u064a\u0641\u0629 \u0648\u0627\u062d\u062f\u0629 \u0627\u0633\u062a\u062e\u062f\u0627\u0645 \u0627\u0644\u0633\u062a\u064a\u0631\u0648\u064a\u062f\u0627\u062a \u0627\u0644\u0645\u0648\u0636\u0639\u064a\u0629\u061b \u0648\u0644\u0645 \u064a\u062d\u062a\u062c 14 \u0645\u0646 \u0623\u0635\u0644 15 \u0645\u0631\u064a\u0636\u064b\u0627 \u062a\u0645 \u0639\u0644\u0627\u062c\u0647\u0645 \u0625\u0644\u0649 \u0625\u062f\u0627\u0631\u0629 \u0645\u0633\u062a\u0645\u0631\u0629 \u0644\u0644\u0627\u0644\u062a\u0647\u0627\u0628 \u0641\u064a \u0627\u0644\u0623\u0633\u0628\u0648\u0639 152.<\/li><\/ul><p>&#8220;These long-term results underscore the lasting impact of MCO-010 in\u00a0patients who\u00a0currently\u00a0have no treatment options,&#8221; said\u00a0<a href=\"https:\/\/nanostherapeutics.com\/ar\/who-we-are\/sulagna-bhattcharya\/\" target=\"_blank\" rel=\"nofollow noopener\">\u0633\u0648\u0644\u0627\u062c\u0646\u0627 \u0628\u0647\u0627\u062a\u0627\u0634\u0627\u0631\u064a\u0627\u060c \u0627\u0644\u0631\u0626\u064a\u0633\u0629 \u0627\u0644\u062a\u0646\u0641\u064a\u0630\u064a\u0629 \u0644\u0634\u0631\u0643\u0629 \u0646\u0627\u0646\u0648\u0633\u0643\u0648\u0628 \u062b\u064a\u0631\u0627\u0628\u064a\u0648\u062a\u0643\u0633.<\/a>\u00a0&#8220;As we advance our rolling Biologics License Application (BLA) with the FDA for MCO-010 in RP, we are actively preparing for a potential commercial launch of what could become the first approved optogenetic therapy for retinal disease. The treatment durability observed in REMAIN also highlights\u00a0the potential of our platform as a one-time therapy for a broad range of retinal\u00a0degenerative\u00a0conditions.&#8221;<\/p><p>\u062a\u0645 \u0639\u0631\u0636 \u0646\u062a\u0627\u0626\u062c \u062f\u0631\u0627\u0633\u0629 REMAIN \u0645\u0624\u062e\u0631\u0627\u064b \u0641\u064a \u0627\u0644\u0639\u062f\u064a\u062f \u0645\u0646 \u0627\u0644\u0645\u0624\u062a\u0645\u0631\u0627\u062a \u0627\u0644\u0631\u0627\u0626\u062f\u0629 \u0641\u064a \u0637\u0628 \u0627\u0644\u0639\u064a\u0648\u0646\u060c \u0628\u0645\u0627 \u0641\u064a \u0630\u0644\u0643:<\/p><ul type=\"disc\"><li>\u0627\u0644\u0627\u062c\u062a\u0645\u0627\u0639 \u0627\u0644\u0633\u0646\u0648\u064a \u0644\u0644\u0623\u0643\u0627\u062f\u064a\u0645\u064a\u0629 \u0627\u0644\u0623\u0645\u0631\u064a\u0643\u064a\u0629 \u0644\u0637\u0628 \u0627\u0644\u0639\u064a\u0648\u0646 (AAO) \u0644\u0639\u0627\u0645 2025 (18-20 \u0623\u0643\u062a\u0648\u0628\u0631 2025) \u2013\u00a0<i>\u0623\u0644\u064a\u0646 \u0633\u064a. \u0647\u0648\u060c \u062f\u0643\u062a\u0648\u0631 \u0641\u064a \u0627\u0644\u0637\u0628\u060c \u0645\u0633\u062a\u0634\u0641\u0649 \u0648\u064a\u0644\u0632 \u0644\u0644\u0639\u064a\u0648\u0646\u060c \u0641\u064a\u0644\u0627\u062f\u0644\u0641\u064a\u0627\u060c \u0628\u0646\u0633\u0644\u0641\u0627\u0646\u064a\u0627<\/i><\/li><li>Retina Society&#8217;s 58<sup>\u0630<\/sup>\u00a0\u0627\u0644\u0627\u062c\u062a\u0645\u0627\u0639 \u0627\u0644\u0639\u0644\u0645\u064a \u0627\u0644\u0633\u0646\u0648\u064a (10-13 \u0633\u0628\u062a\u0645\u0628\u0631 2025) \u2013\u00a0<i>\u0643\u0631\u064a\u0633\u062a\u064a\u0646 \u0643\u0627\u064a\u060c \u0637\u0628\u064a\u0628\u0629\u060c \u062c\u0645\u0639\u064a\u0629 \u0641\u064a\u062a\u0631\u064a\u0648 \u0631\u064a\u062a\u064a\u0646\u0627\u0644\u060c \u063a\u064a\u0646\u0632\u0641\u064a\u0644\u060c \u0641\u0644\u0648\u0631\u064a\u062f\u0627<\/i><\/li><li>25<sup>\u0630<\/sup>\u00a0\u0645\u0624\u062a\u0645\u0631 \u064a\u0648\u0631\u064a\u062a\u064a\u0646\u0627 (4-7 \u0633\u0628\u062a\u0645\u0628\u0631 2025) \u2013\u00a0<i>\u062c\u0648\u0631\u062f\u064a \u0645\u0648\u0646\u064a\u0633\u060c \u062f\u0643\u062a\u0648\u0631\u0627\u0647 \u0641\u064a \u0627\u0644\u0637\u0628\u060c \u062f\u0643\u062a\u0648\u0631\u0627\u0647\u060c \u0645\u0639\u0647\u062f \u0627\u0644\u0628\u0642\u0639\u0629 \u0627\u0644\u0635\u0641\u0631\u0627\u0621\u060c \u0628\u0631\u0634\u0644\u0648\u0646\u0629\u060c \u0625\u0633\u0628\u0627\u0646\u064a\u0627<\/i><\/li><\/ul><p><b>\u062d\u0648\u0644 \u0645\u0646\u0635\u0629 \u0625\u062f\u0627\u0631\u0629 \u0623\u0648\u0627\u0645\u0631 \u0627\u0644\u0642\u064a\u0627\u062f\u0629<br class=\"dnr\" \/><\/b>MCO \u0639\u0628\u0627\u0631\u0629 \u0639\u0646 \u0645\u0646\u0635\u0629 \u0639\u0644\u0627\u062c\u064a\u0629 \u062a\u064f\u0639\u0637\u0649 \u0644\u0645\u0631\u0629 \u0648\u0627\u062d\u062f\u0629 \u0641\u064a \u0627\u0644\u0639\u064a\u0627\u062f\u0629\u060c \u0648\u062a\u064f\u062d\u0642\u0646 \u062f\u0627\u062e\u0644 \u0627\u0644\u062c\u0633\u0645 \u0627\u0644\u0632\u062c\u0627\u062c\u064a \u0644\u0644\u0639\u064a\u0646\u060c \u0648\u0647\u064a \u0645\u0635\u0645\u0645\u0629 \u0644\u0627\u0633\u062a\u0639\u0627\u062f\u0629 \u0627\u0644\u0628\u0635\u0631 \u0644\u062f\u0649 \u0627\u0644\u0645\u0631\u0636\u0649 \u0627\u0644\u0630\u064a\u0646 \u064a\u0639\u0627\u0646\u0648\u0646 \u0645\u0646 \u062a\u0646\u0643\u0633 \u0627\u0644\u062e\u0644\u0627\u064a\u0627 \u0627\u0644\u0645\u0633\u062a\u0642\u0628\u0644\u0629 \u0644\u0644\u0636\u0648\u0621\u060c \u0628\u0645\u0627 \u0641\u064a \u0630\u0644\u0643 \u0627\u0644\u062a\u0647\u0627\u0628 \u0627\u0644\u0634\u0628\u0643\u064a\u0629 \u0627\u0644\u0635\u0628\u0627\u063a\u064a (RP) \u0648\u0645\u0631\u0636 \u0633\u062a\u0627\u0631\u063a\u0627\u0631\u062f\u062a (SD) \u0648\u0627\u0644\u0636\u0645\u0648\u0631 \u0627\u0644\u062c\u063a\u0631\u0627\u0641\u064a (GA). \u064a\u0639\u0645\u0644 MCO \u0639\u0646 \u0637\u0631\u064a\u0642 \u062a\u0646\u0634\u064a\u0637 \u0627\u0644\u062e\u0644\u0627\u064a\u0627 \u062b\u0646\u0627\u0626\u064a\u0629 \u0627\u0644\u0642\u0637\u0628 \u0639\u0627\u0644\u064a\u0629 \u0627\u0644\u0643\u062b\u0627\u0641\u0629 \u0641\u064a \u0627\u0644\u0634\u0628\u0643\u064a\u0629 \u0644\u062a\u0635\u0628\u062d \u062d\u0633\u0627\u0633\u0629 \u0644\u0644\u0636\u0648\u0621\u060c \u0645\u0633\u062a\u0641\u064a\u062f\u064b\u0627 \u0645\u0646 \u0627\u0644\u062f\u0648\u0627\u0626\u0631 \u0627\u0644\u0628\u0635\u0631\u064a\u0629 \u0627\u0644\u0645\u062a\u0628\u0642\u064a\u0629 \u0628\u0639\u062f \u0645\u0648\u062a \u0627\u0644\u062e\u0644\u0627\u064a\u0627 \u0627\u0644\u0645\u0633\u062a\u0642\u0628\u0644\u0629 \u0644\u0644\u0636\u0648\u0621. \u0644\u0627 \u064a\u062a\u0637\u0644\u0628 \u0639\u0644\u0627\u062c MCO \u0627\u062e\u062a\u0628\u0627\u0631\u0627\u062a \u062c\u064a\u0646\u064a\u0629 \u0623\u0648 \u062c\u0631\u0627\u062d\u0629 \u063a\u0627\u0632\u064a\u0629 \u0623\u0648 \u062c\u0631\u0639\u0627\u062a \u0645\u062a\u0643\u0631\u0631\u0629\u060c \u0645\u0645\u0627 \u064a\u062a\u064a\u062d \u062a\u0637\u0628\u064a\u0642\u0647 \u0639\u0644\u0649 \u0646\u0637\u0627\u0642 \u0648\u0627\u0633\u0639 \u0645\u0646 \u0627\u0644\u0645\u0631\u0636\u0649 \u0636\u0645\u0646 \u0625\u062c\u0631\u0627\u0621\u0627\u062a \u0627\u0644\u0639\u0645\u0644 \u0627\u0644\u062d\u0627\u0644\u064a\u0629 \u0641\u064a \u0639\u064a\u0627\u062f\u0627\u062a \u0627\u0644\u0634\u0628\u0643\u064a\u0629.<\/p><p>\u062a\u0645 \u0645\u0646\u062d MCO-010<b>\u00a0\u062a\u0635\u0646\u064a\u0641 \u0627\u0644\u0645\u0633\u0627\u0631 \u0627\u0644\u0633\u0631\u064a\u0639 \u0648\u062f\u0648\u0627\u0621 \u0627\u0644\u064a\u062a\u064a\u0645 \u0645\u0646 \u0642\u0628\u0644 \u0625\u062f\u0627\u0631\u0629 \u0627\u0644\u063a\u0630\u0627\u0621 \u0648\u0627\u0644\u062f\u0648\u0627\u0621 \u0627\u0644\u0623\u0645\u0631\u064a\u0643\u064a\u0629<\/b>\u060c \u0648\u00a0<b>\u0637\u0644\u0628 \u062a\u0631\u062e\u064a\u0635 \u0628\u064a\u0648\u0644\u0648\u062c\u064a \u0645\u062a\u062c\u062f\u062f (BLA)<\/b>\u00a0\u064a\u062c\u0631\u064a \u062d\u0627\u0644\u064a\u0627\u064b \u0625\u062c\u0631\u0627\u0621 \u062f\u0631\u0627\u0633\u0629 \u0644\u0639\u0644\u0627\u062c \u0627\u0644\u062a\u0647\u0627\u0628 \u0627\u0644\u0634\u0628\u0643\u064a\u0629 \u0627\u0644\u0635\u0628\u0627\u063a\u064a.\u00a0<b>\u0648\u0643\u0627\u0644\u0629 \u0627\u0644\u0623\u062f\u0648\u064a\u0629 \u0627\u0644\u0623\u0648\u0631\u0648\u0628\u064a\u0629<\/b><b>\u0648\u0642\u062f \u0645\u0646\u062d\u062a MCO-010 \u062e\u0645\u0633\u0629 \u062a\u0635\u0646\u064a\u0641\u0627\u062a \u0644\u0644\u0623\u064a\u062a\u0627\u0645.<\/b>\u00a0\u0639\u0628\u0631 \u0637\u064a\u0641 \u0648\u0627\u0633\u0639 \u0645\u0646 \u062d\u0627\u0644\u0627\u062a \u062a\u0646\u0643\u0633 \u0627\u0644\u0634\u0628\u0643\u064a\u0629 \u0627\u0644\u062a\u064a \u062a\u0634\u0645\u0644 \u0641\u0642\u062f\u0627\u0646 \u0627\u0644\u062e\u0644\u0627\u064a\u0627 \u0627\u0644\u0645\u0633\u062a\u0642\u0628\u0644\u0629 \u0644\u0644\u0636\u0648\u0621.<\/p><p><b>\u0646\u0628\u0630\u0629 \u0639\u0646 \u0634\u0631\u0643\u0629 \u0646\u0627\u0646\u0648\u0633\u0643\u0648\u0628 \u062b\u064a\u0631\u0627\u0628\u064a\u0648\u062a\u0643\u0633<br class=\"dnr\" \/><\/b>\u062a\u0639\u0645\u0644 \u0634\u0631\u0643\u0629 Nanoscope Therapeutics \u0639\u0644\u0649 \u062a\u0637\u0648\u064a\u0631 \u0639\u0644\u0627\u062c \u0628\u0635\u0631\u064a \u0648\u0631\u0627\u062b\u064a \u0644\u0627\u0633\u062a\u0639\u0627\u062f\u0629 \u0627\u0644\u0628\u0635\u0631\u060c \u0628\u063a\u0636 \u0627\u0644\u0646\u0638\u0631 \u0639\u0646 \u0646\u0648\u0639 \u0627\u0644\u0645\u0631\u0636\u060c \u0644\u0645\u0644\u0627\u064a\u064a\u0646 \u0627\u0644\u0645\u0631\u0636\u0649 \u0627\u0644\u0630\u064a\u0646 \u0641\u0642\u062f\u0648\u0627 \u0628\u0635\u0631\u0647\u0645 \u0628\u0633\u0628\u0628 \u0623\u0645\u0631\u0627\u0636 \u062a\u0646\u0643\u0633\u064a\u0629 \u0641\u064a \u0627\u0644\u0634\u0628\u0643\u064a\u0629. \u0648\u0630\u0644\u0643 \u0628\u0639\u062f \u0627\u0644\u0646\u062a\u0627\u0626\u062c \u0627\u0644\u0625\u064a\u062c\u0627\u0628\u064a\u0629 \u0627\u0644\u062a\u064a \u062d\u0642\u0642\u062a\u0647\u0627 \u062a\u062c\u0631\u0628\u0629 RESTORE \u0627\u0644\u0633\u0631\u064a\u0631\u064a\u0629 \u0645\u062a\u0639\u062f\u062f\u0629 \u0627\u0644\u0645\u0631\u0627\u0643\u0632\u060c \u0627\u0644\u0639\u0634\u0648\u0627\u0626\u064a\u0629\u060c \u0645\u0632\u062f\u0648\u062c\u0629 \u0627\u0644\u062a\u0639\u0645\u064a\u0629\u060c \u0648\u0627\u0644\u0645\u0636\u0628\u0648\u0637\u0629 \u0628\u0627\u0644\u063a\u0641\u0644\u060c \u0645\u0646 \u0627\u0644\u0645\u0631\u062d\u0644\u0629 2\u0628\/3\u060c \u0644\u0639\u0644\u0627\u062c \u0627\u0644\u062a\u0647\u0627\u0628 \u0627\u0644\u0634\u0628\u0643\u064a\u0629 \u0627\u0644\u0635\u0628\u0627\u063a\u064a (RP) (<a href=\"https:\/\/clinicaltrials.gov\/study\/NCT04945772\" target=\"_blank\" rel=\"nofollow noopener\">NCT04945772<\/a>\u0628\u062f\u0623\u062a \u0627\u0644\u0634\u0631\u0643\u0629 \u0625\u062c\u0631\u0627\u0621\u0627\u062a \u062a\u0642\u062f\u064a\u0645 \u0637\u0644\u0628 \u062a\u0631\u062e\u064a\u0635 \u0628\u064a\u0648\u0644\u0648\u062c\u064a (BLA) \u0625\u0644\u0649 \u0625\u062f\u0627\u0631\u0629 \u0627\u0644\u063a\u0630\u0627\u0621 \u0648\u0627\u0644\u062f\u0648\u0627\u0621 \u0627\u0644\u0623\u0645\u0631\u064a\u0643\u064a\u0629 (FDA). \u0641\u064a \u062d\u0627\u0644 \u0627\u0644\u0645\u0648\u0627\u0641\u0642\u0629\u060c \u064a\u064f\u062d\u062a\u0645\u0644 \u0623\u0646 \u064a\u0635\u0628\u062d MCO-010 \u0627\u0644\u0639\u0644\u0627\u062c \u0627\u0644\u0642\u064a\u0627\u0633\u064a \u0644\u0645\u0631\u0636\u0649 \u0627\u0644\u062a\u0647\u0627\u0628 \u0627\u0644\u0634\u0628\u0643\u064a\u0629 \u0627\u0644\u0635\u0628\u0627\u063a\u064a (RP)\u060c \u062d\u064a\u062b \u064a\u064f\u0639\u0637\u0649 \u0643\u062d\u0642\u0646\u0629 \u0648\u0627\u062d\u062f\u0629 \u0641\u064a \u0627\u0644\u0639\u064a\u0627\u062f\u0629 \u062f\u0648\u0646 \u0627\u0644\u062d\u0627\u062c\u0629 \u0625\u0644\u0649 \u0627\u062e\u062a\u0628\u0627\u0631\u0627\u062a \u062c\u064a\u0646\u064a\u0629. \u0643\u0645\u0627 \u0623\u0638\u0647\u0631\u062a \u0627\u0644\u0634\u0631\u0643\u0629 \u0646\u062a\u0627\u0626\u062c \u0648\u0627\u0639\u062f\u0629 \u0641\u064a \u0627\u0644\u0645\u0631\u062d\u0644\u0629 \u0627\u0644\u062b\u0627\u0646\u064a\u0629 \u0645\u0646 \u0627\u0644\u062a\u062c\u0631\u0628\u0629 \u0627\u0644\u0633\u0631\u064a\u0631\u064a\u0629 STARLIGHT \u0644\u0640 MCO-010 \u0641\u064a \u0639\u0644\u0627\u062c \u0645\u0631\u0636 \u0633\u062a\u0627\u0631\u063a\u0627\u0631\u062f\u062a (SD).<a href=\"https:\/\/clinicaltrials.gov\/study\/NCT05417126\" target=\"_blank\" rel=\"nofollow noopener\">NCT05417126<\/a>) \u0648\u062a\u062e\u0637\u0637 \u0644\u0628\u062f\u0621\u00a0<a href=\"https:\/\/nanostherapeutics.com\/ar\/2024\/09\/12\/nanoscope-therapeutics-announces-end-of-phase-2-meeting-with-u-s-fda-and-plan-to-initiate-a-phase-3-clinical-trial-of-mco-010-to-treat-stargardt-macular-degeneration\/\" target=\"_blank\" rel=\"nofollow noopener\">\u0627\u0644\u0645\u0631\u062d\u0644\u0629 \u0627\u0644\u062b\u0627\u0644\u062b\u0629 \u0645\u0646 \u0627\u0644\u062a\u062c\u0631\u0628\u0629 \u0627\u0644\u062a\u0633\u062c\u064a\u0644\u064a\u0629<\/a>\u00a0\u0641\u064a \u0639\u0627\u0645 2025\u060c \u062d\u0635\u0644 \u062f\u0648\u0627\u0621 MCO-010 \u0639\u0644\u0649 \u062a\u0635\u0646\u064a\u0641\u0627\u062a \u0627\u0644\u0645\u0633\u0627\u0631 \u0627\u0644\u0633\u0631\u064a\u0639 \u0648\u062f\u0648\u0627\u0621 \u0627\u0644\u064a\u062a\u064a\u0645 \u0645\u0646 \u0625\u062f\u0627\u0631\u0629 \u0627\u0644\u063a\u0630\u0627\u0621 \u0648\u0627\u0644\u062f\u0648\u0627\u0621 \u0627\u0644\u0623\u0645\u0631\u064a\u0643\u064a\u0629 \u0644\u0639\u0644\u0627\u062c \u0643\u0644 \u0645\u0646 \u0627\u0644\u062a\u0647\u0627\u0628 \u0627\u0644\u0634\u0628\u0643\u064a\u0629 \u0627\u0644\u0635\u0628\u0627\u063a\u064a (RP) \u0648\u0645\u0631\u0636 \u0636\u0645\u0648\u0631 \u0627\u0644\u0634\u0628\u0643\u064a\u0629 (SD)\u060c \u0628\u0627\u0644\u0625\u0636\u0627\u0641\u0629 \u0625\u0644\u0649 \u062a\u0635\u0646\u064a\u0641 RMAT \u0644\u0645\u0631\u0636 \u0636\u0645\u0648\u0631 \u0627\u0644\u0634\u0628\u0643\u064a\u0629\u060c \u0648\u062a\u0635\u0646\u064a\u0641\u0627\u062a \u062f\u0648\u0627\u0621 \u0627\u0644\u064a\u062a\u064a\u0645 \u0645\u0646 \u0648\u0643\u0627\u0644\u0629 \u0627\u0644\u0623\u062f\u0648\u064a\u0629 \u0627\u0644\u0623\u0648\u0631\u0648\u0628\u064a\u0629 (EMA) \u0644\u062a\u063a\u0637\u064a\u0629 \u0636\u0645\u0648\u0631 \u0627\u0644\u0634\u0628\u0643\u064a\u0629 \u063a\u064a\u0631 \u0627\u0644\u0645\u062a\u0644\u0627\u0632\u0645\u064a \u0648\u0627\u0644\u0645\u062a\u0644\u0627\u0632\u0645\u064a \u0627\u0644\u0630\u064a \u064a\u0647\u064a\u0645\u0646 \u0641\u064a\u0647 \u0627\u0644\u062e\u0644\u0627\u064a\u0627 \u0627\u0644\u0639\u0635\u0648\u064a\u0629 \u0648\u0627\u0644\u0645\u062e\u0631\u0648\u0637\u064a\u0629\u060c \u0641\u0636\u0644\u0627\u064b \u0639\u0646 \u0636\u0645\u0648\u0631 \u0627\u0644\u0628\u0642\u0639\u0629 \u0627\u0644\u0635\u0641\u0631\u0627\u0621. \u0648\u0645\u0646 \u0627\u0644\u0645\u062a\u0648\u0642\u0639 \u0623\u0646 \u064a\u0628\u062f\u0623 \u0628\u0631\u0646\u0627\u0645\u062c \u0627\u0644\u0645\u0631\u062d\u0644\u0629 \u0627\u0644\u062b\u0627\u0646\u064a\u0629 \u0644\u062f\u0648\u0627\u0621 MCO \u0641\u064a \u0639\u0644\u0627\u062c \u0627\u0644\u0636\u0645\u0648\u0631 \u0627\u0644\u062c\u063a\u0631\u0627\u0641\u064a (GA) \u0628\u062d\u0644\u0648\u0644 \u0646\u0647\u0627\u064a\u0629 \u0639\u0627\u0645 2025. \u0648\u062a\u0634\u0645\u0644 \u0627\u0644\u0628\u0631\u0627\u0645\u062c \u0627\u0644\u0623\u062e\u0631\u0649 \u0627\u0644\u062c\u0627\u0647\u0632\u0629 \u0644\u062a\u0642\u062f\u064a\u0645 \u0637\u0644\u0628\u0627\u062a \u0627\u0644\u0623\u062f\u0648\u064a\u0629 \u0627\u0644\u062c\u062f\u064a\u062f\u0629 (IND) \u0639\u0644\u0627\u062c \u0627\u0644\u0639\u0645\u0649 \u0627\u0644\u062e\u0644\u0642\u064a \u0644\u0644\u064a\u0628\u0631 (LCA).<\/p><p><b>\u0627\u062a\u0635\u0627\u0644:<br class=\"dnr\" \/><\/b>\u0634\u0631\u0643\u0629 \u0646\u0627\u0646\u0648\u0633\u0643\u0648\u0628 \u062b\u064a\u0631\u0627\u0628\u064a\u0648\u062a\u064a\u0643\u0633<br class=\"dnr\" \/>+1 (817) 857-1186<br class=\"dnr\" \/><a href=\"mailto:PR@nanostherapeutics.com\" target=\"_blank\" rel=\"nofollow noopener\">PR@nanostherapeutics.com<\/a><\/p><p>\u0627\u0644\u0645\u0635\u062f\u0631 \u0639\u0644\u0627\u062c\u0627\u062a \u0627\u0644\u0646\u0627\u0646\u0648<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\r\n\t\t\t\t<\/div>\r\n\t\t\t\t\t\t\t\t<\/div>\r\n\t\t\t<\/section>\r\n\t\t\t\t\t<\/div>","protected":false},"excerpt":{"rendered":"<p>REMAIN results showed sustained, 3-line vision gains vs baseline through 152 weeks for MCO-010 in patients having severe vision loss from retinitis pigmentosa, and a favorable safety profile The data form the clinical basis of a rolling Biologics License Application, initiated in June 2025, with the potential to be the first FDA-approved optogenetic therapy MCO [&hellip;]<\/p>\n","protected":false},"author":6,"featured_media":8971,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_exactmetrics_skip_tracking":false,"footnotes":"","_links_to":"","_links_to_target":""},"categories":[13,8],"tags":[],"class_list":["post-9812","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-home-page","category-nanoscope-press-release"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v28.2 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Nanoscope Therapeutics Announces Durable 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Nanoscope has developed MCO-010, the first and only broad spectrum, fast response and ultra-sensitive optogenetic technology for vision restoration that is gene-agnostic.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/nanostherapeutics.com\/ar\/2025\/10\/22\/nanoscope-therapeutics-announces-durable-3-year-vision-improvements-from-remain-study-of-mco-010-in-retinitis-pigmentosa\/\" \/>\n<meta property=\"og:locale\" content=\"ar_AR\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Nanoscope Therapeutics Announces Durable 3-Year Vision Improvements from REMAIN Study of MCO-010 in Retinitis Pigmentosa - Nanoscope Therapeutics\" \/>\n<meta property=\"og:description\" content=\"Our multi-characteristic opsin (MCO) platform is the first to demonstrate an ability to restore vision to retinal disease patients with severe vision loss in clincial trials. 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