About

Nanoscope Therapeutics is a clinical-stage biopharmaceutical company developing gene therapies to cure genetic diseases that cause vision impairment and blindness.

These diseases include Retinitis Pigmentosa, Dry Age-related Macular Degeneration (AMD), and Stargardt Disease. We are developing a proprietary platform technology, employing ambient light-sensitive Multi-Characteristic Opsins (MCO) that has potential to treat a broad range of genetic illnesses.

Nanoscope Therapeutics, Inc.
1312 Brown Trail, Suite A
Bedford, TX 76022
(817) 857-1186
  • Dr. Samarendra Mohanty, PhD |  Co-Founder & President

    Samarendra Mohanty (Co-Founder/President) is an inventor & serial entrepreneur with 20+ years experience in Biomedical Sciences. He is Co-Founder of several Biotechs and Biomedical device /diagnostic companies (developed & commercialized $100K+ biomedical instruments.)

    Samar obtained M.Tech in Applied Optics from the Indian Institute of Technology-Delhi and a PhD in (Bio)Physics from the Indian Institute of Sciences-Bangalore.

    His extensive Biomedical Technologies experience includes serving as Professor/Senior Scientist at the University of Texas;  University of California, Irvine; Center for Adv. Tech (India); Int. Mol. Biotech (Germany); Univ. Pavia (Italy); NUS (Singapore); and University of St. Andrews (UK). He has authored over 200 international patents and publications in leading journals including Nature and Nature Photonics.

    He is the Principal Investigator for major grants from National Eye Institute including Audacious Goal Initiative and Bioengineering Research grants. He serves on the editorial board of journals and chairs international conference on optogenetics. He is winner of 2019 Healthcare Heroes award (Fort Worth Business Press), Retinal Organoid Challenge Award, Audacious Goal Initiative Award (NIH), Finalist of Tech Titan, and NIH-Director’s Innovator Award.

  • Sulagna Bhattacharya |  Co-Founder & CEO

    Sulagna Bhattacharya has decades of experience in management consulting  at Delliotte and Hitachi Consulting with specialties in business intelligence and risk management. Her expertise includes market research, product and business development, planning including budgeting and forecasting. She played a key role in seven full life cycle project implementations including two multi-billion dollar mergers and acquisitions.
    She is a serial entrepreneur having co-founded several Biotechs and Biomedical device/diagnostic companies. She has authored multiple publications and international patents patents. She is winner of Healthcare Heroes award in 2019.
  • Dr. Aaron Osborne, MBBS |  Chief Medical Officer and Chief Development Officer

    Dr. Osborne has over 20 years’ experience in ophthalmology. Most recently, he served as Chief Medical Officer at Adverum while previously he held clinical development and medical affairs roles of increasing responsibility at Genentech/ Roche, Alcon, Novartis and Bayer. Dr. Osborne earned his medical degree at University College London, before becoming a member of the Royal College of Ophthalmologists in 2004. Subsequently he began his career as a drug developer and has since successfully advanced multiple retinal therapeutic programs.

  • Anthony T. Togba, CPA, CGMA | CFO

    Anthony T. Togba has about 30 years of professional experience in finance, banking, insurance, taxation and accounting. He began his career in public accounting at Coopers & Lybrand (now, Pricewaterhouse Coopers)and he has held several leadership positions including former President/CEO ofMeridien BIAO Bank (Liberia) Limited.

    Anthony is a CPA licensed in Texas. He is also a Certified Global ManagementAccountant (CGMA) and holds an MBA from the Arizona State University. He is a member of the American Institute of Certified Public Accountants and the Texas Society of CPAs

     

     

  • Jared Stephens | VP Strategy and Business Development

    Jared Stephens leads global strategy and business development for Nanoscope Therapeutics.  Prior to joining Nanoscope, Jared served as Director of Strategy, Search & Evaluation for GE Healthcare with responsibility for inorganic growth strategies across the Cell & Gene Therapy and Genomics business units.  In that capacity, Jared led multiple deals to bring adjacent high growth technologies into the GE fold.

    Jared has also severed in corporate strategy and leadership roles at multiple startups including Absci and Bionano genomics, both of which went on to IPO and achieve $B plus market caps.  A cell biologist by training, Jared holds a PhD in Cell and Molecular Biology from the University of California, Irvine.

  • Michelle Carpenter  |  VP Regulatory Affairs

    Ms. Carpenter is a senior management leader and regulatory advisor with more than 25 years of experience gaining global approvals for drugs and biologics for companies ranging from start-up to Fortune 500.  She has a keen interest in developing treatments for orphan diseases and has extensive experience in ophthalmology (neovascular and dry macular degeneration, Stargardt Disease) and gene therapy (neovascular macular degeneration, sickle cell disease).  Ms. Carpenter has held numerous Senior/Vice President roles in Regulatory Affairs, Quality Affairs and Project Management and has worked at True North and Afferent Pharmaceuticals, Sanofi, Santen, and Merck.  She also teaches Regulatory Affairs certification courses for the UC Santa Cruz Bioscience Program and has managed a successful consulting firm.  She earned her Juris Doctorate, with emphasis in Health Law and Ethics, from Golden Gate University and Bachelor’s degree from University of California at Santa Barbara.

  • Hayley Lane  |  VP Clinical Operations

    Ms. Lane has over 25 years of experience in the Pharma/Biotech industry in clinical operations and project management. She has served as VP of Clinical Operations at Adverum Biotechnologies and has held leadership positions at Genentech, Avalanche, Geron, Pfizer and Sanofi. Her extensive experience in Clinical Operations of phase II-IV trials includes preparation of IB, ICF, CSR, annual safety update reports, eDC as well as IND,BLA, CTA filings. She has vast experience in CRO Management, Training of Clinical Project Leaders and Clinical Research Site Managers (CRSMs).

  • Anil Lalwani | VP CMC and Quality

    Anil Lalwani has over 25 years of technical, CMC-centric industry experience with a focus on phase-appropriate products development that meets or exceeds contemporary regulatory expectations. He leveraged his industry experience in academia to help translational (bench-to-clinic) programs with CMC, QA, and FDA engagement for autologous cell therapy and implantable neuromodulation devices for spinal cord injury and pain, a gene therapy (AAV2) for retinal dystrophy (LHON), and allogeneic bone marrow and umbilical cord-derived mesenchymal stem cell products for neurological diseases.

    Anil’s recent regulatory CMC experiences at Allergan (now AbbVie) on a CRISPR/Cas9 gene therapy program, his track record, and his passion for helping unmet need patients adds depth and breadth to Nanoscope’s growing team and portfolio.

    Anil holds a BSc in Mechanical Engineering from Rutgers University, an MSc in Biotechnology Engineering from the University of Pennsylvania, and an MBA in Health Care from the University of Miami.

  • Dr. Kissaou Tchedre | Director of Biopharmaceutical Operations

    Dr. Kissaou Tchedre is Director of Biopharmaceutical Operations at Nanoscope, supporting our Development programs on Gene therapy from preclinical to clinical studies. He has management responsibilities for manufacturing and analytical operations. He is a Biomedical Scientist with decades of experience in commercial Occular Medical Device development at Menicon, a Japanese pharma/medical devices company. He got his MS in molecular biology and a PhD in Biomedical Sciences at the UNTHSC.

    Dr. Tchedre did his post doc at Schepens Eye Research Institute at Harvard Medical School. He has international R&D and business experience in Japan, France and Switzerland.

  • Dr. Ananta Ayyagari | Director of IP and Project Manager

    Dr. Ananta Ayyagari is Director of IP and Project Manager at Nanoscope, supporting our Intellectual Property Development and managing vision restoration projects working closely with preclinical, clinical, CMC and regulatory teams. After completing her doctoral degree in Chemistry, Dr. Ayyagari carried out Postdoctoral fellowship at the Georgia Institute of Technology and the University of Wisconsin-Madison. Her expertise includes development of methods for drug and gene delivery. She has authored several papers and patents.

  • Dr. Subrata Batabyal | Director of Non-clinical Development

    Dr. Subrata Batabyal is Director of Non-clinical Development, leading the pre-clinical research and assay development for Nanoscope’s gene therapy platforms. He earned a PhD in Chemistry investigating biomolecular interactions, followed by Postdoctoral research in biophotonics, focused on optogenetics, gene delivery and optical detection of neuronal activation. He has authored several key papers on cell and gene therapy.

  • John Koester | Global Head of Biostatistics and Clinical Data Management

    Mr. Koester has over 30 years of experience in the pharmaceutical industry. He has worked in ophthalmology clinical development for most of his career and has been a key team member of numerous successful NDAs in wet AMD, glaucoma, ocular allergy, ocular inflammation, and ocular pain. He has also worked on numerous projects in dry AMD, dry eye and Stargardt disease. Mr. Koester served as the Global Head of Biostatistics and Clinical Data Management at CIBA Vision/Novartis Ophthalmics and held senior-level positions at Novartis Pharmaceuticals, Acucela Inc., and Othera Pharmaceuticals.

  • Dr. Al Guillem | Chairman of the Board

    Dr. Al Guillem, Chairman of the Board, is a veteran of the pharmaceutical industry with nearly 40 years of leadership experience in bringing new therapies to the market and readying pharmaceutical manufacturing facilities for commercial production at both well-established and startup companies. Al holds a BSc in Chemistry from the University of Mary Washington and a PhD in Chemistry from Virginia Commonwealth University. Al brings a deep knowledge and insight into pharmaceutical manufacturing across many dosage forms and manufacturing operations. Heheld senior positions at Genzyme/Bone Care, Wyeth (Pfizer), and Boeringher Ingelheim, as well as at start-up companies such as Medeva Americas and Adams Respiratory Therapeutics (ARXT), where he, along with other team members, brought the Mucinex product line to the market. ARXT was sold to Reckitt Benckiser for $2.3 billion in 2007.  Al co-founded and held the role of President and CEO of ZS Pharma, a start-up company developing a product for hyperkalemia or high levels of potassium in the blood. ZS Pharma was acquired by Astra Zeneca in 2015 for $2.7 billion.  Al is currently the CEO of Renibus Therapeutics and he also serves as Chairman of the Board of Onconano Medicine, a pharmaceutical startup engaged in the development of a new class of products that exploit pH as a biomarker to diagnose and treat cancer with high specificity.

  • Dr. Naveed Shams, MD, PhD |  Advisor

    Dr. Shams was most recently the Chief Science Officer at ProQR Therapeutics. He has previously served as President and CEO of Santen Inc, and Global Head of R&D at Santen Pharmaceuticals, a global ophthalmology company, for over a decade. Dr. Shams has over 25 years of global drug development experience across start-ups and large multinationals, including Novartis and Genentech/Roche. At Genentech, Dr. Shams helped to establish the Ophthalmic Clinical R&D Group and led the development of Lucentis® through approval. Previously, Dr. Shams was on the Faculty at the Department of Ophthalmology, Harvard Medical School. He holds an MD from Dow Medical College and a PhD in microbiology/immunology from the University of South Carolina and completed a fellowship in wound healing and corneal transplantation at Harvard University.

  • Dr. Thomas Ciulla, MD |  Advisor

    Dr. Ciulla is Chief Medical Officer and Chief Development Officer at Clearside Biomedical, where he supported approval of the first suprachoroidal therapy (Xipere), led an IND submission for development of a new clinical program (CLS-AX, a Suprachoroidal TKI), strategically guides preclinical development, and supports numerous external partnerships, including gene therapy. He previously served a VP role at Spark Therapeutics, where he led medical strategy to support approval and commercialization of Luxturna, the first FDA-approved gene therapy for a hereditary disease, which involved novel functional vision endpoints, complex genetic testing paradigms, new administration procedures at ocular gene therapy treatment centers, and unique reimbursement pathways associated with one-time orphan gene therapies.

    Prior to Spark Therapeutics, he served a VP role, in Clinical Strategy at Ophthotech (now Iveric Bio), where he contributed to clinical protocol and analysis plan development for the successful phase 3 trial of Zimura in Geographic Atrophy (OPH2003, now GATHER1). Previously, he was Co-Director of the retina service and tenured Associate Professor at Indiana University, the largest US medical school; he remains a volunteer Clinical Professor, as well as board member at Midwest Eye Institute. Dr. Ciulla graduated from Harvard College and UCSF Medical School, followed by an internship and residency at Harvard Medical School, fellowship at Tufts Medical School, and an MBA from Indiana University’s Kelley School of Business, specializing in the business of medicine.