- Chief Medical Officer Dr. Sam Barone to join the Emerging Innovations in Retinal Therapies panel; Company to present an update on MOGENRY®in the Retina Drug Delivery New Targets Showcase at Eyecelerator 2026.
- Four-year REMAIN data from the RESTORE Phase 2b/3 trial of MCO-010 in retinitis pigmentosa and a scientific poster on dry AMD to be presented at the AAO 2026 Annual Meeting, October 8–13, 2026, in New Orleans, Louisiana.
دالاس, Oct. 6, 2026 / بي آر نيوزواير / — علاجات النانوسكوب, Inc., a biotechnology company committed to developing and commercializing novel, disease-agnostic therapies for patients with photoreceptor loss and vision impairment due to retinal degeneration, today announced that its optogenetics gene therapy (MOGENRY, MCO-010) will be featured in various scientific programming at the American Academy of Ophthalmology (AAO) 2026 annual meeting taking place October 8–13, 2026, in New Orleans. Additionally, the company will participate in Eyecelerator@AAO 2026 with a company presentation and panel participation. Eyecelerator brings together ophthalmic innovators, industry leaders, clinicians, and investors to accelerate the development of new therapies and technologies in eye care. The AAO Annual Meeting is the world’s largest gathering of ophthalmologists and eye care professionals.
Eyecelerator Presentation Details:
Eyecelerator 2026, Ernest N. Morial Convention Center
لوحة: Emerging Innovations in Retinal Therapies
المتحدث: Sam Barone, MD, Chief Medical Officer
التاريخ والوقت: Thursday, October 8, 2026, 10:45–11:30 AM CT
موقع: La Nouvelle Ballroom C
Company Presentation: Retina Drug Delivery & New Targets Showcase
مقدم: Paul Hallen, Chief Operating Officer
التاريخ والوقت: Thursday, October 8, 2026, 1:00–1:05 PM CT
موقع: Rooms 252–254
AAO Presentation Details:
AAO 2026 Annual Meeting, Ernest N. Morial Convention Center
عرض تقديمي: Lasting vision Improvement in Retinitis Pigmentosa: REMAIN 4-Year Study Data From the RESTORE Phase 2b/3 Trial of MCO-010 Optogenetic Therapy
حصة: PA044
مقدم: Kenneth C. Fan, MD
التاريخ والوقت: Sunday, October 11, 2026, 11:42–11:49 AM CT
موقع: Rooms 255–257
Scientific Poster: Vision Improvement in Dry AMD With Sonpiretigene Isteparvovec Optogenetic Therapy: First Direct-to-Phase 2 RCT
حصة: PO624
مقدم: David S. Boyer, MD
Availability: On demand
During the panel, Dr. Barone will join fellow industry leaders to discuss emerging approaches in retinal therapeutics, including the potential of mutation-agnostic optogenetic gene therapy for patients with advanced retinal degeneration. In the Showcase presentation, Mr. Hallen will provide an update on Nanoscope’s progress toward potential global approval of its lead asset, MOGENRY® (سونبيريتيجيني إستيبارفوفيك; MCO-010), for the treatment of inherited retinal dystrophies, including the status of the Company’s Biologics License Application (BLA), و Japan New Drug Application (JNDA), currently under FDA and PMDA review respectively. At AAO 2026, Dr. Fan will present four-year data from the REMAIN study of patients treated in the RESTORE Phase 2b/3 trial, highlighting the durability of vision improvement with MCO-010 in retinitis pigmentosa. Dr. David S. Boyer will also present a scientific poster, available on demand, on vision improvement with sonpiretigene isteparvovec in dry AMD from the first direct-to-Phase 2 randomized controlled trial. Members of the Nanoscope leadership team will be available to meet with retina specialists, investors, and potential partners throughout Eyecelerator and AAO 2026.
Nanoscope team members will be available at Booth 2564 for the duration of the AAO conference.
حول MOGENRY (sonpiretigene isteparvovec؛ MCO-010)
Nanoscope’s multi-characteristic opsin (MCO) technology utilizes a proprietary genetically engineered synthetic opsin to enable optimized performance in terms of high light sensitivity across a broad spectrum and fast kinetics. After Nanoscope’s Co-Founder, President, and Chief Scientific Officer, Samarendra Mohanty, envisioned and invented the technology, his team has spent over a decade evaluating its performance across multiple animal models and human diseases. MOGENRY is an investigational, one-time, in-office, intravitreal optogenetic gene therapy built on Nanoscope’s MCO platform. By delivering a multi-characteristic opsin gene to the highly dense bipolar retinal cells, MOGENRY makes these surviving cells directly light-sensitive, enabling them to utilize the remaining visual circuitry following photoreceptor loss. MOGENRY does not require genetic testing, invasive surgery, or repeat dosing, and is designed for administration within existing retina office workflows. MOGENRY is under review by the FDA for the treatment of RP with severe vision loss and under priority review by the PMDA and MHLW for the treatment of IRDs in Japan. The 2026 Nobel Prize in Physiology or Medicine was recently awarded to the three scientists who pioneered optogenetics, the scientific foundation that Nanoscope’s development programs, including MOGENRY, are built upon.
نبذة عن شركة نانوسكوب ثيرابيوتكس
تعمل شركة Nanoscope Therapeutics على تطوير علاج بصري وراثي لاستعادة البصر، بغض النظر عن نوع المرض، لملايين المرضى الذين فقدوا بصرهم بسبب أمراض تنكس الشبكية. وذلك بعد النتائج الإيجابية التي حققتها تجربة RESTORE السريرية متعددة المراكز، العشوائية، مزدوجة التعمية، والمضبوطة بالغفل، من المرحلة 2ب/3، لعلاج التهاب الشبكية الصباغي (RP).NCT04945772)، ال FDA has accepted and filed the Company’s BLA for MOGENRY, and the PMDA has accepted for priority review the Company’s NDA for MOGENRY for the treatment of IRDs in Japan. If approved, MOGENRY has the potential to become the standard of care for patients with RP and other IRDs, administered as a one-time, in-office injection without the need for genetic testing. The Company has also shown promising results in the STARLIGHT Phase 2 clinical trial of MCO-010 in Stargardt disease (SD) (NCT05417126وتخطط الشركة لبدء المرحلة الثالثة من التجارب السريرية للتسجيل في عام 2026. وقد حصل دواء MCO-010 على تصنيفات المسار السريع ودواء اليتيم من إدارة الغذاء والدواء الأمريكية لعلاج كل من التهاب الشبكية الصباغي (RP) ومرض ضمور الشبكية (SD)، بالإضافة إلى تصنيف RMAT لمرض ضمور الشبكية، وتصنيفات دواء اليتيم من وكالة الأدوية الأوروبية (EMA) التي تغطي ضمور الشبكية غير المتلازمي والمتلازمي الذي يهيمن فيه الخلايا العصوية والمخروطية، فضلاً عن ضمور البقعة الصفراء. كما حصل MCO-010 على تصنيفات ساكيغاكي ودواء اليتيم لضمور الشبكية الوراثي في اليابان، وتصنيف دواء اليتيم لضمور الشبكية الوراثي في المملكة العربية السعودية. ومن المتوقع أن يبدأ برنامج المرحلة الثانية لدواء MCO لعلاج الضمور الجغرافي في عام 2026، وتشمل البرامج الأخرى الجاهزة لتقديم طلبات الأدوية الجديدة (IND) علاج العمى الخلقي لليبر (LCA).
Learn more at NanosTherapeutics.com and follow @NSTherapeutics on X and on LinkedIn.
اتصال:
شركة نانوسكوب ثيرابيوتكس
(817) 857-1186
PR@nanostherapeutics.com
المصدر علاجات النانو